ID POSITIVE TEST POSITIVE TRAIN NEG TEST NEG TRAIN [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases 7 6 49 49 [J] COG0017 Aspartyl/asparaginyl-tRNA synthetases 12 11 20 20 [J] COG0024 Methionine aminopeptidase 7 6 33 36 [G] COG0061 Predicted sugar kinase 8 7 30 29 "[K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit" 10 10 29 30 "[K] COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit" 16 15 31 30 [J] COG0101 Pseudouridylate synthase 6 5 29 29 [J] COG0102 Ribosomal protein L13 7 6 29 29 "[BQ] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein" 9 9 19 18 [H] COG0142 Geranylgeranyl pyrophosphate synthase 10 10 50 50 [J] COG0144 tRNA and rRNA cytosine-C5-methylases 17 16 32 31 [EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D 8 7 24 25 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI) 7 6 39 38 [J] COG0293 23S rRNA methylase 5 5 15 16 [R] COG0388 Predicted amidohydrolase 11 10 53 52 [L] COG0417 DNA polymerase elongation subunit (family B) 14 14 9 10 [M] COG0438 Glycosyltransferase 58 58 186 186 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases 21 20 124 124 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases 29 29 241 243 [R] COG0456 Acetyltransferases 12 12 44 44 [R] COG0457 FOG: TPR repeat 43 43 212 213 [O] COG0459 Chaperonin GroEL (HSP60 family) 14 13 48 47 [FE] COG0462 Phosphoribosylpyrophosphate synthetase 7 7 31 31 [O] COG0464 ATPases of the AAA+ class 19 19 34 35 [L] COG0468 RecA/RadA recombinase 13 13 31 30 [L] COG0470 ATPase involved in DNA replication 18 18 36 36 [CE] COG0473 Isocitrate/isopropylmalate dehydrogenase 8 7 30 30 [P] COG0474 Cation transport ATPase 6 5 41 41 [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 6 6 37 37 [GEPR] COG0477 Permeases of the major facilitator superfamily 129 129 639 640 [J] COG0480 Translation elongation factors (GTPases) 7 7 42 41 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes 15 15 152 153 [QR] COG0500 SAM-dependent methyltransferases 90 90 303 303 [F] COG0516 IMP dehydrogenase/GMP reductase 9 8 60 61 [R] COG0517 FOG: CBS domain 68 67 98 97 [J] COG0522 Ribosomal protein S4 and related proteins 7 7 31 31 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins 25 25 154 153 [E] COG0531 Amino acid transporters 35 35 93 94 "[KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family" 5 5 49 50 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 17 16 223 225 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases 7 6 47 47 "[C] COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K" 7 7 31 32 "[O] COG0638 20S proteasome, alpha and beta subunits" 16 15 25 23 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases 9 9 46 48 "[R] COG0656 Aldo/keto reductases, related to diketogulonate reductase" 9 8 41 38 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) 7 6 70 70 [I] COG0671 Membrane-associated phospholipid phosphatase 7 7 53 53 [J] COG0689 RNase PH 5 5 20 19 [R] COG0693 Putative intracellular protease/amidase 9 8 47 46 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily 27 27 166 166 [T] COG0784 FOG: CheY-like receiver 25 24 247 249 "[V] COG0842 ABC-type multidrug transport system, permease component" 22 22 78 78 [R] COG1011 Predicted hydrolase (HAD superfamily) 16 15 52 51 [C] COG1012 NAD-dependent aldehyde dehydrogenases 15 15 164 164 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 26 26 387 386 [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases 6 5 41 40 [R] COG1100 GTPase SAR1 and related small G proteins 11 10 47 46 [G] COG1109 Phosphomannomutase 13 13 61 60 [L] COG1112 Superfamily I DNA and RNA helicases and helicase subunits 8 7 22 23 "[V] COG1131 ABC-type multidrug transport system, ATPase component" 47 47 115 114 "[V] COG1132 ABC-type multidrug transport system, ATPase and permease components" 6 5 146 145 "[MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)" 20 20 26 24 [J] COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing 8 8 10 12 "[L] COG1241 Predicted ATPase involved in replication control, Cdc46/Mcm family" 12 12 11 10 [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily 8 7 21 20 [J] COG1358 Ribosomal protein HS6-type (S12/L30/L7a) 7 6 14 14 [O] COG1404 Subtilisin-like serine proteases 7 6 46 46 "[K] COG1594 DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS" 9 8 6 6 [J] COG1841 Ribosomal protein L30/L7E 7 6 23 24 [K] COG1958 Small nuclear ribonucleoprotein (snRNP) homolog 11 11 22 22 [B] COG2036 Histones H3 and H4 10 9 11 10 [L] COG2801 Transposase and inactivated derivatives 16 16 191 192